Science-Backed Healthy Weight Management

Start your journey with a naturally-derived product that burns fat, not muscle, and helps you keep it off for good.

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Benefits of using motus

Human study weight loss results similar to injectables*
Targets fat loss while sparing lean muscle mass*
Supports healthy metabolism and liver health*
Optimizes energy expenditure*

study participant before & after's

swipe through the cards below to see the real benefits that Motus can have on your weight loss journey

John

weight before Motus: 230 lbs

weight after Motus: 218 lbs

Emma

weight before Motus: 140 lbs

weight after Motus: 116 lbs

Scott

weight before Motus: 303 lbs

weight after Motus: 271 lbs

Shawna

weight before Motus: 238 lbs

weight after Motus: 203.6 lbs

Dave

weight before Motus: 231 lbs

weight after Motus: 192 lbs

Kim

weight before Motus: 165 lbs

weight after Motus: 142.8 lbs

Research Studies

Read about our ingredient's peer-reviewed research studies

Nicotinamide is a precursor to NAD⁺, which supports mitochondrial function, insulin usage, and energy metabolism. NAD⁺ decline is associated with poor health, and replenishment may promote metabolic efficiency. ***

*1

"Nicotinamide Riboside Enhances Muscle Mitochondrial Biogenesis in Humans” – Cell Metabolism, 2016 → Showed increased NAD⁺ levels and improved mitochondrial biogenesis in skeletal muscle.

*2

“Nicotinamide Improves Glucose Metabolism and Insulin Sensitivity in
Pre-Diabetic Subjects” – Diabetologia, 2019 → Demonstrated improved glucose tolerance and insulin signaling markers.

*3

“Supplementation with NAD⁺ Precursors in Obesity and Type 2 Diabetes: A Review” – Nutrients, 2023 → Summarized metabolic benefits of NAD⁺ restoration in obese individuals.

Taurine regulates glucose metabolism, improves mitochondrial health, and reduces adipogenesis. It may also increase energy expenditure and improve lipid profiles in overweight individuals. ***

*1

“Taurine Supplementation Reduces Weight and Improves Lipid Profile in Obese Women” – Clinical Nutrition, 2012 → A 30-day trial showed significant weight and triglyceride reduction with 3g/day taurine.

*2

“Taurine Supplementation Improves Inflammation and Lipid Profiles in Obese Individuals” – Food & Function, 2016 → Reported reduced C-reactive protein and improved cholesterol parameters.

*3

“The Role of Taurine in Glucose Homeostasis and Energy Metabolism”
– Molecular Nutrition & Food Research, 2021 → Reviewed evidence of taurine’s role in metabolic regulation in humans and animals.

Siliphos is a highly bioavailable form of silybin (milk thistle), a flavonolignan with liver-supporting and insulin related effects. It plays a critical role in metabolic management. ***

*1

“Silybin-Phosphatidylcholine Complex Reduces Liver Fat and Insulin Resistance in NAFLD Patients” – Hepatology, 2007 → Demonstrated improvements in insulin sensitivity and liver enzyme normalization.

*2

“Silymarin Improves Metabolic Profile in Obese Patients with Type 2 Diabetes” – Phytotherapy Research, 2014 → Noted reductions in fasting glucose, insulin, and waist circumference.

*3

“Silybin Reduces Oxidative Stress and Improves Liver Function in Overweight Adults” – Journal of Clinical Gastroenterology, 2021 → Shown to reduce hepatic inflammation markers.

Berberine activates AMPK, supporting glucose metabolism and lipid regulation. Berberine supports insulin signaling and supports weight loss. ***

*1

“Berberine Improves Insulin Sensitivity and Body Composition in Obese Humans” – Metabolism: Clinical and Experimental, 2012 → Demonstrated improved insulin sensitivity and body weight in a 12- week RCT.

*2

“A Systematic Review and Meta-Analysis of Berberine for Metabolic Syndrome” – Obesity Reviews, 2020 → Found consistent reductions in BMI, fasting glucose, triglycerides, and waist circumference.

*3

“Comparison of Berberine and Metformin in Patients with Type 2
Diabetes” – Journal of Clinical Endocrinology & Metabolism, 2008 → Found equivalent effects on HbA1c, fasting blood glucose, and triglycerides.

ALA is a mitochondrial antioxidant that supports insulin signaling, supports antioxidant processes, and supports weight loss by modulating glucose uptake and energy utilization. ***

*1

“Alpha-Lipoic Acid Supplementation Reduces Weight and Improves
Insulin Sensitivity in Overweight Subjects” – American Journal of Clinical Nutrition, 2011 → 1,800 mg/day led to ~2.1 kg greater weight loss vs. placebo in 20 weeks.

*2

“Effect of Alpha-Lipoic Acid on Body Weight and Glycemic Control in Overweight Women with PCOS” –Gynecological Endocrinology, 2014 → Showed reductions in weight, fasting insulin, and HOMA-IR.

*3

“Meta-Analysis of ALA for Weight Loss in Humans” – Obesity Reviews, 2018 → ALA supplementation resulted in a mean weight loss of ~1.5 kg over 8–12 weeks.

Discovering Motus

Our decade of research and testing with Duke University unveiled a powerful natural safe and effective weight loss supplement.

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* The results were based on a non-IND 100 person human study conducted over 6 months.
This research and these statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.